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Obagi Nu-Derm

When you are a baby, your skin is perfect. It is soft, firm and glows with health. But as you mature, usually sometime in your 30’s, your skin begins to lose its ability to stay healthy. Collagen breaks down. The skin loses its elasticity. Cell turnover and the flow of moisture from deep within begins to slow. The damage gets worse from sun, stress, environmental assaults and smoking. The results may be tight, dry, blotchy skin. Even wrinkles and discoloration may develop.

The goal of the Obagi Nu-Derm System is to create soft, radiant-looking skin, to increase skin tolerance to environmental assault and to restore normal skin functions. The Obagi Nu-Derm System corrects surface discoloration and blemishes. Importantly, it also penetrates into the skin to stimulate skin cell renewal, improve circulation and help rebuild collagen. The normal barrier function of the skin is restored, making the skin less sensitive and better able to hydrate properly. After six weeks (one skin cycle), new skin cells emerge to the surface.

The Obagi Nu-Derm System (available at AYA in Atlanta, GA) recognizes that the skin is a living organ with interacting functions. Overall skin health cannot be achieved if the treatment is aimed just at the elimination of a single skin symptom. To restore and maintain skin health, the program must address the causes of the problem and solve them. The Obagi Nu-Derm System of correction and stimulation will:
obagi before and after

The Obagi Nu-Derm System utilizes the most effective prescription treatments for hyperpigmentation and the effects of photodamage to improve your skin at the cellular level.

Gentle Cleanser

A dissolving cleanser recommended for cleaning normal to dry, sensitive skin. It helps remove impurities, make-up, dead skin cells, and excess oil without irritating the skin. This formulation is designed to clean the skin surface and pores gently and effectively. Wash the face morning and evening with the cleanser.

Foaming Gel

Recommended for normal to oily skin. It deep cleans the skin and removes excess oil without stripping it of moisture. Wash the face morning and evening with the gel.


A applied after cleansing the skin. This restores the skin’s natural pH, enhances the action of the cleansers, and prepares the skin for the Correct and Stimulate steps. Unlike most toners, the Obagi Toner formulation does not dry the skin excessively. This formulation is designed to tighten the skin and pores. The toner should be applied after the skin is cleansed to the entire face avoiding the upper and lower lids of the eyes. Do not rinse off.


Clear is the major bleaching and correcting preparation in the program. It contains 4% Hydroquinone (prescription strength) as the active ingredient in an activating base to increase its effectiveness. Bleaching with hydroquinone suppresses the overproduction of melanin. Clear is to be used twice daily until the expected results have been achieved. Thereafter, it is to be used as needed to maintain results. Apply Clear to the entire face, morning and evening, avoiding the eyelids, extended to the hairline, over the ears and ending with a feathering motion from the jawline down the neck. A second coat can be applied over darker pigmented lesions. Patients with dark skin should use Clear on the entire face once a day, preferably in the morning and apply at night on the darkest areas only.

Exfoderm Forte

Exfoderm Forte is the product used in the system for exfoliation and to help enhance the hydroquinone and tretinoin activity. It contains AHA’s: lactic acid and glycolic acid. Exfoderm Forte is indicated for thick, oily, large pores, and/or rough skin. Apply Exfoderm Forte evenly over entire face avoiding the eyelid area. It is to be applied in the morning after the application of Clear. It may occasionally cause stinging upon application.


Exfoderm contains phytic acid which is gentler than AHAs. It helps with keratolytic and exfoliating activity. It also helps enhance the activity of hydroquinone and tretinoin. Exfoderm is indicated for dry, thin, or sensitive skin and is to be applied in the morning after the application of Clear. Apply Exfoderm evenly over entire face avoiding the eyelid area.


To be coordinated with Blender. Tretinoin .5% should be sold to patients with dry/sensitive/combination skin to start out with. They can then work their way up to 1%. Tretinoin 1% should be sold to patients with oily/thick skin.


Blender contains a specific formulation of 4% hydroquinone and an activating base that complements retinoin activity and provides blending along with stimulation. Apply evenly to the entire face, avoiding the eyelids, extending to the hairline, over the ears and ending with a feathering motion from the jawline down the neck.

Obagi Professional-C Serum

Attacks free oxygen radicals. In addition to its function as a powerful antioxidant, Vitamin C also encourages the production of collagen and elastin. Used daily, Obagi Professional-C Serums can help restore the luster and youthfulness that time has taken away. Contains L-ascorbic acid, the most potent form of Vitamin C the body uses to combat oxy-radicals. Available in 5% for the eye area, 10% for dry, sensitive, or reactive skin, 15% for all skin types, and 20% for the highest concentration of L-ascorbic acid.

obagi crx

Obagi-C RX

The patented combination of prescription strength 4% Hydroquinone and professional strength Vitamin C (L-Ascorbic Acid) is the first and only system of its kind. It is well documented that Vitamin C has substantial benefits in preventing the skin’s accelerated aging process due to sunlight, smoking and other contaminants. Hydroquinone has long been considered the gold standard for treating uneven skin tone.

C-RX Clarifying Serum
The first and only prescription strength 4% Hydroquinone and Vitamin C Serum. It penetrates deep into the skin’s dermal layers, where it enhances collagen production and reduces melanosome activity and tyrosinase activation, making skin Photolumines. Contains 4% Hydroquinone, 10% L-Ascorbic Acid.

Obagi Hydrate Moisturzier

The latest edition to Obagi®’s medical grade skin products, Hydrate, is a moisturizing lotion formulated to provide long-lasting results for up to 8 hours. Unlike other facial moisturizers, Obagi® Hydrate contains Hydromanil, a technologically advanced ingredient that retains water to continuously deliver moisture to all of the skin’s layers. Along with Hydromanil, Obagi® Hydrate also contains shea butter, mango butter, and avocado oil to combat dryness without clogging pores.

Hydrate is dermatologist-tested and clinically proven to be safe and beneficial for skin. This moisturizer is designed to complement the Obagi Nu-Derm® system and can be easily integrated into other skincare regimens.


Obagi CLENZIderm M.D.TM prescription-strength acne therapeutic system is the only acne treatment with a liquid form of benzoyl peroxide. This system is clinically proven to provide visibly clearer kin as early as 2 weeks. It is easy to use and does not require the use of an antibiotic. As a result, you can use CLENZIderm M.D.TM as long as needed without having to worry about developing a resistance to antibiotics.

CLENZIderm M.D. Normal to Oily Skin System includes:

Step 1: Cleanse – Daily Care Foaming Cleanser
Removes dirt and excess oil with 2% salicylic acid, leaving skin clean and refreshed.

Step 2: Prepare – Pore Therapy
Unclogs pores and clears dead skin cells while preparing skin to deeply absorb a liquefied serum that targets acne at its source.

Step 3: Treat – Serum Gel
Potent gel turns to liquid serum on contact. Delivers liquefied bensoyl peroxide deep within your pores where acne starts. Quickly clears acne and prevents new breakouts from occurring.

CLENZIderm M.D.TM Normal to Dry Skin System includes:

Step 1: Cleanse – Daily Care Cream Cleanser
Gentle, non-soap cleanser removes dirt and excess oil, leaving skin clean and soft..

Step 2: Prepare – Therapeutic Lotion
5% solubilized BPO lotion quickly clears acne and prevents new breakouts without drying the skin.

Step 3: Treat – Therapeutic Moisturizer
Non-comedogenic, glycerin-rich moisturizer. Calms, soothes and protects skin to enhance patient comfort.

Shop Obagi skincare at our online store

The doctors at AYA Medical Spa have either authored or reviewed the content on this site. Page Last Updated: